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Industrial and Enterprise Systems Engineering

Where data, design and decision-making converge.

Academic Programs

When you join ISE at Grainger Engineering, you join a community where big ideas meet bold collaboration. At Illinois, you’ll design data-driven solutions, lead cross-disciplinary teams and shape innovations that make industries—and lives—work better.

Preparing to go to college for the first time or looking to transfer from another institution? We've got you covered! Explore our degree programs, plan your a visit, prepare to apply and more.

We offer many flexible options, from online graduate programs to certificate programs. Discover the best path for your goals, learn how to apply and find faculty in your field.

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Industrial and Enterprise Systems Engineers at Work

From inspired thinking to real impact — explore the stories of ISE.

Researchers develop novel wearable knee rehabilitation device in international collaboration

ISE News
May 26, 2026

Researchers from the University of Illinois Urbana-Champaign, Vietnam’s VinUniversity and UNSW Sydney created KNEESENSE, a wearable rehabilitation system that uses a soft hydraulic sensor to track knee movement during recovery exercises. Designed to be lightweight, wireless and affordable, the device pairs with a mobile app to provide real-time feedback and support at-home rehabilitation, particularly in areas with limited access to physical therapy services. The project highlights ongoing international collaboration through the VinUni-Illinois Smart Health Center.

2026 ISE Student Conference: Showcasing innovation in data-driven intelligent systems

ISE News
May 11, 2026

The Department of Industrial and Enterprise Systems Engineering at the University of Illinois Urbana-Champaign hosted the 3rd Annual ISE Student Conference on April 24, 2026, bringing together students, faculty, and researchers for a day of presentations focused on data-driven intelligent systems and real-world impact. The event featured keynote talks from Nagi Gebraeel and Navid Azizan, followed by an evening poster session and networking reception.

When data doesn’t play by the rules: Illinois researchers find a new path to stability in AI-era data markets

ISE News
May 7, 2026

Researchers from the Grainger College of Engineering's Department of Industrial and Enterprise Systems Engineering found that traditional pricing models fail in data markets because datasets can be sold repeatedly without being depleted, making stable pricing difficult to achieve. Their ICML 2026 Spotlight paper shows that allowing prices to vary based on purchase quantity can restore market stability, offering a practical framework for the rapidly growing AI and data economy.

When decisions shape uncertainty: Illinois researchers advance a new frontier in optimization

ISE News
May 4, 2026

Two ISE Faculty Honored for Excellence in Teaching

ISE News
April 15, 2026

Chrysafis Vogiatzis and Avinash Gupta, are being recognized for excellence in teaching with campus- and college-level awards reflect a shared commitment to student-centered innovation and the impact of mentorship within ISE.

An ISE alum's path to transforming healthcare

ISE News
March 30, 2026

An Illinois ISE alum traces her journey from optimizing hospital scheduling as a graduate student to shaping medical device data standards at the FDA and beyond — showing students how systems engineering can drive meaningful change across an entire healthcare ecosystem.

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Research for a Better World

From smarter systems to sustainable solutions, our research creates real impact. See how ISE is engineering change.

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Faculty

ISE faculty are leaders in advancing human-centered systems, data analytics and optimization. Their groundbreaking research and cross-disciplinary collaborations drive innovation in fields ranging from healthcare and manufacturing to sustainability and artificial intelligence.

Meet the Faculty

Alumni

From Fortune 500 companies to cutting-edge startups, ISE alumni are shaping how the world works. Their Illinois experience empowers them to lead with insight, optimize with impact and build a better future wherever they go.

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